Chemistry lessons

Debra Messing

TV hit: “Will & Grace” (1998-2006)

Rom-com debut: “The Wedding Date” (2005)

Hot or not: Lukewarm. The modest $31 million gross hardly set Messing up as the next Julia Roberts, but at least the movie made its $15 million budget back.

Up next: Messing presumably plays to her strengths with a supporting role in the female-driven ensemble comedy-drama “The Women,” starring Meg Ryan, Eva Mendes, Annette Bening and Jada Pinkett Smith. There’s also talk of turning her hit USA network miniseries “The Starter Wife” into a full-fledged series.